The answer
On many account-based chains, an identical transaction with the same nonce cannot be executed twice once confirmed, but signing and sending a different transaction can create a second payment.
What to do next
Inspect the nonce, transaction hash and confirmed state before retrying a payment or approval.
Etherscan
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Ledger hardware wallet
Relevant hardware-backed signing for supported assets; it does not eliminate gas fees, contract vulnerabilities or approval risks.
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Frequently asked questions
Will pressing Send again always be harmless?
No. A new signed transaction may be a separate transfer; verify the first result.