The answer
Yes. Pool fees, smart-contract risk, exchange-rate movements between paired assets, liquidity changes and withdrawal conditions can change the realised outcome.
What to do next
Compare the exact pool design, withdrawal terms, fees and contract risk rather than treating an advertised APR as a guaranteed return.
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Frequently asked questions
Does an advertised DeFi yield guarantee the final USD value?
No. Returns and principal can change for several independent reasons.